Two pregnancies after simultaneous pancreas–kidney transplantation: A case report. (June 2020)

• Record Type: Journal Article
• Authors: Mohammadi, Fadak; McDonald, Stephen; Clark, Erin; Jesudason, Shilpanjali
• Is Part Of: Obstetric medicine. Volume 13:Number 2(2020:Jun.)
• Page Start: 92
• Page End: 95
• Publication Date: 2020-06
• Subjects: High-risk pregnancy -- kidney -- pancreas -- transplantation -- pre-eclampsia; Pregnancy -- Complications -- Periodicals; Obstetrics -- Periodicals; 618.2
• DOI: 10.1177/1753495X18789584
• Languages: English
• ISSNs: 1753-495X

Abstract

Simultaneous kidney–pancreas transplantation can successfully restore fertility in women with type 1 diabetes mellitus and kidney failure. There have been few cases of pregnancy after simultaneous kidney–pancreas transplantation, and a second pregnancy is rare. We report a case of two live births in rapid succession in a simultaneous kidney–pancreas transplantation recipient, complicated by pre-eclampsia but with excellent fetal and graft outcomes. The first pregnancy was achieved with IVF, while the second was achieved naturally. Simultaneous kidney–pancreas transplantation with stable pre-pregnancy graft function enabled this patient to achieve successful pregnancy. However, both pregnancies were complicated by transient renal graft dysfunction and pre-eclampsia precipitating pre-term birth.