Ultrasound-mediated diagnostic imaging and advanced treatment with multifunctional micro/nanobubbles. (10th April 2020)

• Record Type: Journal Article
• Authors: Li, Jiaping; Xi, Aini; Qiao, Huanhuan; Liu, Zhe
• Is Part Of: Cancer letters. Volume 475(2020)
• Page Start: 92
• Page End: 98
• Publication Date: 2020-04-10
• Subjects: Ultrasound -- Gas-filled bubbles -- Photothermal -- Photodynamic -- Sonodynamic treatment; Cancer -- Periodicals; Neoplasms -- Periodicals; Cancer -- Périodiques; Electronic journals; 616.994
• DOI: 10.1016/j.canlet.2020.01.028
• Languages: English
• ISSNs: 0304-3835

Abstract

Abstract: Ultrasound associated with ultrasound contrast agents has witnessed ever-growing innovations and applications for disease-targeted diagnosis and therapy. With these state-of-the-art technologies, brand-new invasive or minimally invasive treatments are on the way to be clinically translated. This mini-review focuses on the ultrasound and ultrasound-related micro/nanobubbles as multifunctional agents for drug/gene delivery and multi-modality treatments, e.g. photodynamic, sonodynamic and photothermal therapies in a precise and visualized manner. Highlights: The recent advanced biomedical ultrasound technologies has been summarized for their widely applications in the clinics. Gas-filled micro/nanobubbles have been classified for their versatile utilities on the diagnostic imaging and disease-targeted therapy. State-of-the-art ultrasound-based treatments as translationable strategies for fatal diseases of humans have been discussed.