A first case of meningitis/encephalitis associated with SARS-Coronavirus-2. (May 2020)
- Record Type:
- Journal Article
- Title:
- A first case of meningitis/encephalitis associated with SARS-Coronavirus-2. (May 2020)
- Main Title:
- A first case of meningitis/encephalitis associated with SARS-Coronavirus-2
- Authors:
- Moriguchi, Takeshi
Harii, Norikazu
Goto, Junko
Harada, Daiki
Sugawara, Hisanori
Takamino, Junichi
Ueno, Masateru
Sakata, Hiroki
Kondo, Kengo
Myose, Natsuhiko
Nakao, Atsuhito
Takeda, Masayuki
Haro, Hirotaka
Inoue, Osamu
Suzuki-Inoue, Katsue
Kubokawa, Kayo
Ogihara, Shinji
Sasaki, Tomoyuki
Kinouchi, Hiroyuki
Kojin, Hiroyuki
Ito, Masami
Onishi, Hiroshi
Shimizu, Tatsuya
Sasaki, Yu
Enomoto, Nobuyuki
Ishihara, Hiroshi
Furuya, Shiomi
Yamamoto, Tomoko
Shimada, Shinji - Abstract:
- Highlights: Novel coronavirus (SARS-Coronavirus-2:SARS-CoV-2) which emerged in Wuhan, China, has spread to multiple countries rapidly. This is the first case of meningitis associated with SARS-CoV-2 who was brought in by ambulance. The specific SARS-CoV-2 RNA was not detected in the nasopharyngeal swab but was detected in a CSF. This case warns the physicians of patients who have CNS symptoms. Abstract: Novel coronavirus (SARS-Coronavirus-2:SARS-CoV-2) which emerged in Wuhan, China, has spread to multiple countries rapidly. We report the first case of meningitis associated with SARS-CoV-2 who was brought in by ambulance due to a convulsion accompanied by unconsciousness. He had never been to any foreign countries. He felt generalized fatigue and fever (day 1). He saw doctors nearby twice (day 2 and 5) and was prescribed Laninamivir and antipyretic agents, His family visited his home and found that he was unconsciousness and lying on the floor in his vomit. He was immediately transported to this hospital by ambulance (day 9). Under emergency transport, he had transient generalized seizures that lasted about a minute. He had obvious neck stiffness. The specific SARS-CoV-2 RNA was not detected in the nasopharyngeal swab but was detected in a CSF. Anti- HSV 1 and varicella-zoster IgM antibodies were not detected in serum samples. A brain MRI showed hyperintensity along the wall of right lateral ventricle and hyperintense signal changes in the right mesial temporal lobe andHighlights: Novel coronavirus (SARS-Coronavirus-2:SARS-CoV-2) which emerged in Wuhan, China, has spread to multiple countries rapidly. This is the first case of meningitis associated with SARS-CoV-2 who was brought in by ambulance. The specific SARS-CoV-2 RNA was not detected in the nasopharyngeal swab but was detected in a CSF. This case warns the physicians of patients who have CNS symptoms. Abstract: Novel coronavirus (SARS-Coronavirus-2:SARS-CoV-2) which emerged in Wuhan, China, has spread to multiple countries rapidly. We report the first case of meningitis associated with SARS-CoV-2 who was brought in by ambulance due to a convulsion accompanied by unconsciousness. He had never been to any foreign countries. He felt generalized fatigue and fever (day 1). He saw doctors nearby twice (day 2 and 5) and was prescribed Laninamivir and antipyretic agents, His family visited his home and found that he was unconsciousness and lying on the floor in his vomit. He was immediately transported to this hospital by ambulance (day 9). Under emergency transport, he had transient generalized seizures that lasted about a minute. He had obvious neck stiffness. The specific SARS-CoV-2 RNA was not detected in the nasopharyngeal swab but was detected in a CSF. Anti- HSV 1 and varicella-zoster IgM antibodies were not detected in serum samples. A brain MRI showed hyperintensity along the wall of right lateral ventricle and hyperintense signal changes in the right mesial temporal lobe and hippocampus, suggesting the possibility of SARS-CoV-2 meningitis. This case warns the physicians of patients who have CNS symptoms. … (more)
- Is Part Of:
- International journal of infectious diseases. Volume 94(2020)
- Journal:
- International journal of infectious diseases
- Issue:
- Volume 94(2020)
- Issue Display:
- Volume 94, Issue 2020 (2020)
- Year:
- 2020
- Volume:
- 94
- Issue:
- 2020
- Issue Sort Value:
- 2020-0094-2020-0000
- Page Start:
- 55
- Page End:
- 58
- Publication Date:
- 2020-05
- Subjects:
- SARS-CoV-2 -- COVID-19 -- Meningitis -- Infections -- Polymerase chain reaction
Communicable diseases -- Periodicals
Communicable Diseases -- Periodicals
Communicable diseases
Periodicals
Electronic journals
616.9 - Journal URLs:
- http://bibpurl.oclc.org/web/73769 ↗
http://www.journals.elsevier.com/international-journal-of-infectious-diseases/ ↗
http://www.sciencedirect.com/science/journal/12019712 ↗
http://www.clinicalkey.com/dura/browse/journalIssue/12019712 ↗
http://www.clinicalkey.com.au/dura/browse/journalIssue/12019712 ↗
http://www.elsevier.com/journals ↗ - DOI:
- 10.1016/j.ijid.2020.03.062 ↗
- Languages:
- English
- ISSNs:
- 1201-9712
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 4542.304750
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- 13496.xml