Pulmonary tumour thrombotic microangiopathy presented as gastric signet ring cell carcinoma: A case report. Issue 3 (March 2020)

• Record Type: Journal Article
• Authors: Cui, Ning; Wang, Lijun; Zhao, Jingming
• Is Part Of: Journal of international medical research. Volume 48:Issue 3(2020)
• Publication Date: 2020-03
• Subjects: Pulmonary tumour thrombotic microangiopathy -- signet ring cell carcinoma -- pulmonary hypertension -- dyspnoea -- gastric cancer; Medicine -- Periodicals; Pharmacology -- Periodicals; 610.5
• DOI: 10.1177/0300060520910884
• Languages: English
• ISSNs: 0300-0605

Abstract

Pulmonary tumour thrombotic microangiopathy (PTTM) is a rare complication of cancer characterized by widespread tumour cell emboli in small arteries and arterioles of the lung and often accompanied by microthrombi. We report a case of PTTM in a young Chinese woman that presented as gastric signet ring cell carcinoma. Although rare, PTTM should be considered in cancer patients with a rapidly progressing dyspnoea, chest computed tomography (CT) scan suggestive of pulmonary hypertension and diffuse pulmonary interstitial infiltration.