Synthesis of zephycandidine A from haemanthamine. Issue 16 (16th April 2020)

• Record Type: Journal Article
• Authors: Murphy, Patrick J.; Tibble-Howlings, Jamie; Kowalczyk, Radoslaw M.; Stevens, Kevin
• Is Part Of: Tetrahedron letters. Volume 61:Issue 16(2020)
• Publication Date: 2020-04-16
• Subjects: Zephycandidine A -- Phenanthridine -- Trispheridine -- Haemanthamine -- Imidazo[1, 2-f]phenanthridines; Chemistry, Organic -- Periodicals; 547.005
• DOI: 10.1016/j.tetlet.2020.151785
• Languages: English
• ISSNs: 0040-4039

Abstract

Graphical abstract: Highlights: The first reported synthesis of the alkaloid Zephycandidine A. A naturally occurring imidazo[1, 2- f ]phenanthridine alkaloid. Zephycandidine A Prepared in three steps from the naturally occurring alkaloid haemanthamine. Abstract: Zephycandidine A the first naturally occurring imidazo[1, 2– f ]phenanthridine alkaloid, isolated from Zephyranthes candida ( Amaryllidaceae ) has been prepared in three steps from the naturally occurring alkaloid haemanthamine.