Distribution of heart rate and responses to resuscitation among 1237 apnoeic newborns at birth. (July 2020)

• Record Type: Journal Article
• Authors: Eilevstjønn, Joar; Linde, Jørgen E.; Blacy, Ladislaus; Kidanto, Hussein; Ersdal, Hege L.
• Is Part Of: Resuscitation. Volume 152(2020)
• Page Start: 69
• Page End: 76
• Publication Date: 2020-07
• Subjects: HR heart rate -- PPV positive pressure ventilation -- bpm beats per minute -- ECG electrocardiogram -- PIP peak inspiratory pressure; Newborn resuscitation -- Heart rate -- ECG -- Positive pressure ventilation -- Bag-mask; Resuscitation -- Periodicals; Resuscitation -- Periodicals; Réanimation -- Périodiques; Electronic journals; 616.025
• DOI: 10.1016/j.resuscitation.2020.04.037
• Languages: English
• ISSNs: 0300-9572

Abstract

Abstract: Aim of the study: Describe the distribution of the first recorded heart rate (HR) in apnoeic term/near-term newborns, HR responses to basic resuscitation (no intubation, chest compressions and/or medication), and relationship to 24-h outcomes. We also document patient characteristics and care provider behaviour stratified by first HR. Methods: Descriptive study from July 2013 through June 2018 at Haydom Hospital in Tanzania. All deliveries were observed by assistants recording data. Bag-mask ventilation and ECG data were recorded by resuscitation monitors. Newborns with ≥5 ventilations and ECG signal-data were included. Results: 1237 term/near-term newborns with median (25th, 75th percentiles) gestation 38 (37, 40) weeks and birth weight 3140 (2750, 3500) grams fulfilled inclusion criteria. The first HR, measured median 102 (73, 144) s after birth following drying/stimulation, was distributed into two peaks with centres around 60 and 165 bpm, 51% were ≥100 bpm. After ventilation, the HR distribution shifted to a single-peak, with median 161 bpm. At least one low-high HR transition crossing 100 bpm was noted in 44% of newborns. The HR increase occurred over median 9.2 (6.2, 13) s, was 60 (43, 77) bpm, and 86% followed a ventilation sequence of 23 (16, 34) s duration. 72% of the newborns with first HR < 60 bpm survived following ventilations only. Both first and final HR were significantly related to 24-h outcomes. Conclusions: The first recorded HR was distributed into two peaks on each side of 100 bpm. Ventilation increased HR in most newborns. Lower first and final HR were related to gradually more adverse 24-h outcomes.