Effect of intensive self-management education on seizure frequency and quality of life in epilepsy patients with prodromes or precipitating factors. (May 2020)

• Record Type: Journal Article
• Authors: Hu, Meiling; Zhang, Chenqi; Xiao, Xiaoqiang; Guo, Jiang; Sun, Hongbin
• Is Part Of: Seizure. Volume 78(2020)
• Page Start: 38
• Page End: 42
• Publication Date: 2020-05
• Subjects: Epilepsy -- Prodromes -- Precipitating factors -- Self-management education; Epilepsy -- Periodicals; Epilepsy -- Periodicals; Seizures -- Periodicals; Épilepsie -- Périodiques; Electronic journals; Electronic journals; 616.853
• DOI: 10.1016/j.seizure.2020.03.003
• Languages: English
• ISSNs: 1059-1311

Abstract

Highlights: The overall quality of life was improved by intensive self-management education. Intensive self-management education may reduce seizure frequency. The drug adherence of patients was improved by intensive self-management education. Intensive self-management education may reduce accidental injury caused by seizure. Abstract: Purpose: To explore the impact of an intensive self-management education strategy on seizure frequency and quality of life in patients with epileptic seizures with prodromes or precipitating factors. The intensive self-management education included monthly education sessions on prodromes and precipitating factors aiming to help patients to adopt self-management strategies. Methods: Adult patients with epilepsy (PWE) able to identify prodromes or precipitating factors of their seizures were randomly assigned to an intensive education group (IEG) (n = 45) or a regular education group(REG) (n = 47). All patients received a single face-to-face self-management education session at the time of enrollment. Both groups of patients received monthly telephone follow-up for 1 year. PWE in the IEG received intensive education during each follow-up call. Primary outcomes were seizure frequency, quality of life(Quality of life in epilepsy—31 inventory scores, QOLIE 31), and drug adherence(Morisky medication adherence scale, MMAS). Results: At the end of the 1-year follow-up period, seizure frequency in the IEG was significantly lower than at baseline (p < 0.001), but not in the REG(p = 0.085). Quality of life had improved significantly in the IEG (p < 0.001), but not in the REG (p = 0.073). Drug adherence was better in the IEG than in the REG (p = 0.003), and there were fewer accidental injuries in the IEG than the REG (p = 0.031). Conclusions: In PWE aware of seizure prodromes or precipitating factors, intensive self-management education may reduce seizure frequency, improve quality of life, increase adherence with antiepileptic medication and reduce accidental injuries caused by seizures.