Multiple endocrine neoplasia type 2B: Maxillofacial finding in one case. Issue 3 (May 2020)

• Record Type: Journal Article
• Authors: Abdullah, Bashar; Museedi, Omar; Saif, Juma; Basima, Ali; Saja, Malik
• Is Part Of: Journal of oral and maxillofacial surgery, medicine, and pathology. Volume 32:Issue 3(2020)
• Page Start: 233
• Page End: 235
• Publication Date: 2020-05
• Subjects: Multiple endocrine neoplasia type 2B -- MEN 2B -- Oral mucosal neuroma; Mouth -- Surgery -- Periodicals; Face -- Surgery -- Periodicals; Maxilla -- Surgery -- Periodicals; Oral medicine -- Periodicals; Mouth -- Diseases -- Pathogenesis -- Periodicals; Surgery, Oral -- Periodicals; Oral Medicine -- Periodicals; Pathology, Oral -- Periodicals; Face -- Surgery; Maxilla -- Surgery; Mouth -- Diseases -- Pathogenesis; Mouth -- Surgery; Oral medicine; Electronic journals -- Sciences; Electronic journals -- Medicine; Periodicals; 617.522059
• DOI: 10.1016/j.ajoms.2019.11.003
• Languages: English
• ISSNs: 2212-5566

Abstract

Abstract: Multiple Endocrine Neoplasia type 2B (MEN 2B) is a very rare autosomal dominant disease in which the oral lesions may be the first clue that leads to the diagnosis. We describe a case of A 18 year old male diagnosed as MEN 2B due to multiple oral lesions of the tongue and the lips. The presenting feature was a nodular fibrous lesion at a central diastema. Histopathological and Immunohistochemical examination revealed multiple mucosal neuroma. The case report highlights the importance of oral lesions in early detection of such life threatening conditions.