Activity determination of 18F using liquid scintillation beta-efficiency extrapolation and non-extrapolation methods. (June 2020)

• Record Type: Journal Article
• Authors: van Rooy, M.W.; van Staden, M.J.; Simpson, B.R.S.; Lubbe, J.
• Is Part Of: Applied radiation and isotopes. Volume 160(2020:Jun.)
• Publication Date: 2020-06
• Subjects: F-18 -- Liquid scintillation coincidence counting -- Extrapolation -- Non-extrapolation -- Second monopeak -- SIRTI; Radiology -- Periodicals; Radiation -- Industrial applications -- Periodicals; Nuclear chemistry -- Periodicals; Internet resource; Periodical; 660.298
• DOI: 10.1016/j.apradiso.2020.109070
• Languages: English
• ISSNs: 0969-8043

Abstract

Abstract: The absolute activity of 18 F was determined using 4 πβ − γ liquid scintillation coincidence counting using beta-efficiency extrapolation. An ionization chamber factor was determined for use during a SIRTI comparison, for which results are presented. A non-extrapolation method based on a detection efficiency analysis was also employed using an adaptation of the double-phototube coincidence efficiency for a threshold above the second monopeak. Results and uncertainty budgets for the two methods are presented and discussed. Highlights: Absolute standardization of F-18 using beta-efficiency extrapolation and-non extrapolation methods. Liquid scintillation coincidence counting. Double-tube efficiency adapted for threshold above second monopeak for non-extrapolation method. Excellent agreement between the methods.