Comparison between radial versus femoral percutaneous coronary intervention access in Indonesian hospitals, 2017–2018: A prospective observational study of a national registry. (April 2020)

• Record Type: Journal Article
• Authors: Alkatiri, Amir Aziz; Firman, Doni; Haryono, Nur; Yonas, Emir; Pranata, Raymond; Fahri, Ismir; Artha, I Made Junior Rina; Pratama, Vireza; Widodo, Wishnu Aditya; Taufiq, Nahar; Alkatiri, Abdul Hakim; Ng, Sunanto; Sulastomo, Heru; Soerianata, Sunarya
• Is Part Of: IJC heart & vasculature. Volume 27(2020)
• Publication Date: 2020-04
• Subjects: Radial access -- Percutaneous coronary intervention -- National registry -- Indonesia; ACE Angiotensin Converting Enzyme -- AF Atrial Fibrillation -- ARB Angiotensin Receptor Blocker -- AVB Atrioventricular Block -- CAD Coronary Artery Disease -- CKD Chronic Kidney Disease -- CTO Chronic Total Occlusion -- CVD Cerebrovascular Disease -- HF Heart Failure -- LAD Left Anterior Descending -- LBBB Left-bundle Branch Block -- LCX Left Circumflex Artery -- LM Left Main -- PCI Percutaneous Coronary Intervention -- PVD Peripheral Vascular Disease -- MI Myocardial Infarction -- NOAC Non-vitamin K Antagonist Oral Anticoagulant -- NSTEACS Non-ST segment Elevation Acute Coronary Syndrome -- RBBB Right-bundle Branch Block -- RCA Right Coronary Artery -- TIA Transient Ischemic Attack; Cardiovascular system -- Diseases -- Periodicals; Cardiovascular system -- Pathophysiology -- Periodicals; 616.1005
• DOI: 10.1016/j.ijcha.2020.100488
• Languages: English
• ISSNs: 2352-9067

Abstract

Abstract: Background: Coronary heart disease is a leading cause of death in Indonesia and percutaneous coronary intervention (PCI) is a routinely performed procedure. The aim of this study is to provide real-world insight on the demographics of coronary artery disease and comparison between radial compared to femoral PCI in Indonesia, which performed radial access whenever possible. Methods: This is a prospective cohort study involving 5420 patients with coronary artery disease who underwent PCI at 9 participating centers in the period of January 2017–December 2018. Results: Radial access rate was performed in 4038 (74.5%) patients. Patients receiving femoral access has a higher rate of comorbidities and complex lesions compared to radial access. The incidence of in-hospital mortality, cardiogenic shock, major arrhythmia, and tamponade were higher in femoral group. The incidence of in-hospital mortality was 114 (2.1%). New-onset angina (OR 3.412), chronic renal failure (OR 3.47), RBBB (OR 4.26), LBBB (OR 6.26), left main stenosis PCI (OR 3.58), cardiogenic shock (OR 4.9), and arrhythmia (OR 15.59) were found to be independent predictors of in-hospital mortality. Radial access did not independently affect in-hospital mortality. In propensity-matched cohort, radial access was not associated with lower in-hospital mortality in both bivariable and multivariable model. However, radial access was associated with reduced in-hospital mortality in STEMI subgroup (OR 0.31). Conclusion: Higher rate of adverse events was noted on the femoral access group. However, it might stem from the fact that patients with more comorbidities and complex lesions are more likely to be assigned to femoral access-group. Neither radial or femoral access is superior in terms of in-hospital mortality upon propensity-score matching/multivariable analysis.