Bone and joint infections of the hand. (July 2020)

• Record Type: Journal Article
• Authors: Sendi, P.; Kaempfen, A.; Uçkay, I.; Meier, R.
• Is Part Of: Clinical microbiology and infection. Volume 26:Number 7(2020)
• Page Start: 848
• Page End: 856
• Publication Date: 2020-07
• Subjects: Bone and joint infections -- Finger joint infection -- Hand infection -- Osteomyelitis -- Septic arthritis; Medical microbiology -- Periodicals; Diagnostic microbiology -- Periodicals; Communicable diseases -- Periodicals; Infection -- Periodicals; 616.01
• DOI: 10.1016/j.cmi.2019.12.007
• Languages: English
• ISSNs: 1198-743X

Abstract

Abstract: Background: Little guidance is currently available for standardized diagnostic protocols and therapeutic recommendations for bone and joint infections (BJIs) of the hand. Objectives: To summarize the available data in the scientific English-language literature on the diagnosis and treatment of native BJIs of the hand. To illustrate these concepts from a narrative point of view in areas where there is lack of evidence. Sources: We performed a systematic PubMed and Internet search of studies that investigated hand BJIs in adult patients. Content: Few studies have systematically investigated and validated diagnostic concepts, classifications or surgical treatment protocols. Most concepts derive from traditional intra-institutional experience, expert opinions and extrapolations from infections in large joints and long bones. Similarly, there is no uniformly accepted infection definition of BJIs of the hand. The best-documented literature is available for microbiological findings and antibiotic treatment duration in uncomplicated native joint arthritis of the fingers. Retrospective studies and one prospective randomized trial suggest that post-surgical targeted antibiotic therapy of 2 weeks results in a microbiological cure rate of ≥88%. Implications: Studies on diagnostic workup and infection definition and classification are urgently needed to compare inter-institutional outcome results and generate guidelines for the best patient care. For uncomplicated pyogenic arthritis of native joints, current evidence suggests that a 2-week course of antibiotic therapy following surgery cures the infection. Graphical abstract: Image 1