The role of polycaprolactone-triol (PCL-T) in biomedical applications: A state-of-the-art review. (15th May 2020)

• Record Type: Journal Article
• Authors: Abrisham, Mahbod; Noroozi, Mina; Panahi-Sarmad, Mahyar; Arjmand, Mohammad; Goodarzi, Vahabodin; Shakeri, Yasaman; Golbaten-Mofrad, Hooman; Dehghan, Parham; Seyfi Sahzabi, Alireza; Sadri, Mahdi; Uzun, Lokman
• Is Part Of: European polymer journal. Volume 131(2020)
• Publication Date: 2020-05-15
• Subjects: Polycaprolactone-triol -- (bio-) Polymer-based materials -- Biomedical applications -- Tissue engineering -- Shape memory materials -- Drug delivery -- Coating & anti-fouling; Polymers -- Periodicals; Polymerization -- Periodicals; Polymères -- Périodiques; Polymérisation -- Périodiques; Polymerization; Polymers; Periodicals; Electronic journals; 547.705
• DOI: 10.1016/j.eurpolymj.2020.109701
• Languages: English
• ISSNs: 0014-3057

Abstract

Graphical abstract: Highlights: Features of Polycaprolactone-triol (PCL-T) are discussed. We present a comprehensive summary of recent progress in the development of materials containing PCL-T. The materials based on PCL-T preparation methods and assembly strategies of products overviewed. The promising bio-applications of PCL-T are reviewed. Proper final properties can be achieved by engineering chemistry of biomaterials with PCL-T. Abstract: Polycaprolactone triol (PCL-T) is one of the distinguished materials, which recently has been used in a wide range, from fabricating polymeric composites to bio-inspired applications, including tissue engineering, actuators, artificial skin, drug delivery system, and so forth. Bio application makes up approximately all of the health within the living organisms. The biomaterials are required to be sturdy and/or durable in structures such as bones, tendons, and ligaments. Besides, PCL-T being one of the most available alcohols that provide tensile strength (in polyurethane and other materials) via crosslinking interactions to design desirable architecture. Therefore, biomimetic materials containing PCL-T gained widespread acceptance in clinical applications. Indeed, PCL-Ts are regularly utilized for numerous purposes as they offered in a wide range of compositions, characteristics, and intricate structures. Because of polyester-based materials, they have a potential array for biomedical utilizations. Due to versatile features of the elongated fibrils and comprehensive industrial and biomedical utilization, including biocompatibility of PCL-T, this review sheds light on PCL-T-based materials with their likely applications, mainly focusing the bio-medical field.