The overview and prospects of BNCT facility at Tsing Hua Open-pool reactor. (July 2020)

• Record Type: Journal Article
• Authors: Jiang, Shiang-Huei; Hsueh Liu, Yen-Wan; Chou, Fong-In; Liu, Hong-Ming; Peir, Jinn-Jer; Liu, Yuan-Hao; Huang, Yu-Shiang; Wang, Ling-Wei; Chen, Yi-Wei; Yen, Sang-Hue; Wu, Yuan-Hung; Liu, Ching-Sheng; Lee, Jia-Cheng; Chang, Chi-Wei; Wang, Shyh-Jen; Huang, Wen-Sheng; Kai, Ji-Jung
• Is Part Of: Applied radiation and isotopes. Volume 161(2020:Jul.)
• Publication Date: 2020-07
• Subjects: BNCT facility -- THOR -- Overview -- Prospects; Radiology -- Periodicals; Radiation -- Industrial applications -- Periodicals; Nuclear chemistry -- Periodicals; Internet resource; Periodical; 660.298
• DOI: 10.1016/j.apradiso.2020.109143
• Languages: English
• ISSNs: 0969-8043

Abstract

Abstract: The whole picture of the BNCT facility at Tsing Hua Open-pool Reactor will be presented which consists of the following aspects: the construction project, the beam quality, routine operations including the QA program for the beam delivery, determination of boron-10 concentration in blood, T/N ratio, and the clinical affairs including the patient recruit procedure and the patient irradiation procedure. The facility is positioned to serve for conducting clinical trials, emergent (compassionate) treatments, and R&D works. Highlights: THOR has gone into critical since 1961. THOR facility is the only reactor-based facility still clinically active. We have accomplished two clinical trials for recurrent head and neck cancer. 26 patients have been treated with 9 CRs and 4 survivals. THOR BNCT facility is open to the BNCT community all around the world.