Phenoxazinone synthase mimicking activity of a dinuclear copper(II) complex with a half salen type Schiff base ligand. (1st March 2020)

• Record Type: Journal Article
• Authors: Roy, Sourav; Dutta, Tamal; Drew, Michael G.B.; Chattopadhyay, Shouvik
• Is Part Of: Polyhedron. Volume 178(2020)
• Publication Date: 2020-03-01
• Subjects: Copper(II) -- Half salen Schiff base -- Crystal structure -- Phenoxazinone synthase mimicking activity; Chemistry, Inorganic -- Periodicals; Chimie inorganique -- Périodiques; Organometaalverbindingen; Anorganische chemie; 546.05
• DOI: 10.1016/j.poly.2019.114311
• Languages: English
• ISSNs: 0277-5387

Abstract

Graphical abstract: A pseudohalide bridged dinuclear copper(II) complex with a half salen type Schiff base ligand has been synthesized and characterized. Phenoxazinone synthase mimicking activity of the complex has been investigated. Abstract: A dinuclear copper(II) complex [LCu(μ1, 1 -N3 )2 CuL] {where HL = (2-(3-aminopropylimino)methyl-6-methoxyphenol) } has been synthesized and characterized by several analytical techniques including single crystal X-ray diffraction analysis. Interesting supramolecular interactions are observed in the solid state of the complex. An unusual N–H⋯π interaction is observed where the chelate ring, Cu(1)–N(1)–Cu(1) b –N(1) b, [where b = 1 − x, −y, 1 − z] behaves as a π system. Supramolecular interactions have been related with Hirshfeld surface calculations. The complex has been evaluated as functional model for phenoxazinone synthase enzyme by using o -aminophenol (OAPH) as a model substrate in acetonitrile medium. Kinetics of the reaction was followed spectrophotometrically, which confirm that catalytic reactions follow Michaelis–Menten enzymatic reaction kinetics.