Cobalt‐Catalyzed Multi‐Component Reactions: Recent Advances and Perspectives in Organic Synthesis. Issue 25 (1st July 2020)

• Record Type: Journal Article
• Authors: Susan Treesa, G. S.; Neetha, Mohan; Saranya, Salim; Anilkumar, Gopinathan
• Is Part Of: ChemistrySelect. Volume 5:Issue 25(2020)
• Page Start: 7400
• Page End: 7416
• Publication Date: 2020-07-01
• Subjects: Catalysis -- C-heteroatom bond formation -- Cobalt -- Multi-component reaction (MCR) -- One-pot synthesis; Chemistry -- Periodicals; 540.5
• DOI: 10.1002/slct.202002021
• Languages: English
• ISSNs: 2365-6549

Abstract

Abstract: This review focuses on the recent achievements in the field of cobalt‐catalyzed multi‐component reactions that could access a wide range of acyclic compounds, carbocyclic compounds and heterocyclic compounds. Multi‐component reactions (MCRs) gained significant interest in organic synthesis since they could be utilized to achieve complex products from readily available starting materials in an environment‐friendly manner. This review covers the literature up to 2019 and is the first one that emphasizes on cobalt‐catalyzed one‐pot multi‐component reactions. Abstract : Multi‐component reactions are one‐pot operations that are designed as atom‐economic which could provide a diversity‐oriented synthesis of a wide variety of biologically active organic scaffolds. The straightforward access of complex compounds from readily available reactants have made multi‐component reactions (MCRs) of great interest and importance in organic synthesis. Over the past few decades, heterocyclic synthesis by utilizing transition metal‐catalyzed MCRs stirred up the scientific world enhancing researcher's attention. This review emphasizes on cobalt‐catalyzed MCRs and covers the literature up to 2019.