Computer‐aided Drug Design: Additive Manufacturing of a Point‐of‐Care "Polypill:" Fabrication of Concept Capsules of Complex Geometry with Bespoke Release against Cardiovascular Disease (Adv. Healthcare Mater. 13/2020). Issue 13 (8th July 2020) - Pereira, Beatriz C.
Abstract : In article number 2000236 by Enoche F. Oga, Mohamed A. Alhnan, and co‐workers a novel design approach is employed to fabricate highly modular 3D printed "polypill" capsules with bespoke release patterns for multiple drugs. Complex structures are devised to achieve dose individualization. In silico pharmacokinetic projections of the developed capsules highlight how healthcare staff can adapt complex therapeutic regimens to each patient.