On the evolution of the quality of macromolecular models in the PDB. (20th April 2020)

• Record Type: Journal Article
• Authors: Brzezinski, Dariusz; Dauter, Zbigniew; Minor, Wladek; Jaskolski, Mariusz
• Is Part Of: FEBS journal. Volume 287:Number 13(2020)
• Page Start: 2685
• Page End: 2698
• Publication Date: 2020-04-20
• Subjects: nucleic acids -- PDB -- proteins -- structure quality -- X‐ray crystallography; Biochemistry -- Periodicals; Molecular biology -- Periodicals; Pathology, Molecular -- Periodicals; 572
• DOI: 10.1111/febs.15314
• Languages: English
• ISSNs: 1742-464X

Abstract

Abstract : Crystallographic models of biological macromolecules have been ranked using the quality criteria associated with them in the Protein Data Bank (PDB). The outcomes of this quality analysis have been correlated with time and with the journals that published papers based on those models. The results show that the overall quality of PDB structures has substantially improved over the last ten years, but this period of progress was preceded by several years of stagnation or even depression. Moreover, the study shows that the historically observed negative correlation between journal impact and the quality of structural models presented therein seems to disappear as time progresses. Abstract : Quality criteria are proposed to rank the macromolecular models in the Protein Data Bank (PDB), and the results are correlated with time and with the journals that published papers based on those models. The overall quality of PDB structures has substantially improved over the last decade, and the negative correlation between journal impact factor and the quality of structural models presented therein seems to disappear as time progresses.