Macromolecular crystallography beamlines at the Canadian Light Source: building on success. Issue 7 (6th July 2020)

• Record Type: Journal Article
• Authors: Fodje, Michel; Mundboth, Kiran; Labiuk, Shaunivan; Janzen, Kathryn; Gorin, James; Spasyuk, Denis; Colville, Scott; Grochulski, Pawel
• Is Part Of: Acta crystallographica. Volume 76:Issue 7(2020)
• Page Start: 630
• Page End: 635
• Publication Date: 2020-07-06
• Subjects: macromolecular crystallography -- beamline -- double crystal/multi‐layer monochromator -- Canadian Light Source; X-ray crystallography -- Periodicals; Crystallography -- Periodicals; Molecular biology -- Periodicals; Molecular structure -- Periodicals; Biomolecules -- Structure -- Periodicals; Cytology -- Periodicals; Biomolecules -- Structure; Crystallography; Cytology; Molecular biology; Molecular structure; X-ray crystallography; Periodicals; 548
• DOI: 10.1107/S2059798320007603
• Languages: English
• ISSNs: 2059-7983

Abstract

Abstract : The current capabilities of and future upgrade plans for the beamlines supporting structural biology at the Canadian Light Source are described. Abstract : The Canadian Macromolecular Crystallography Facility (CMCF) consists of two beamlines dedicated to macromolecular crystallography: CMCF‐ID and CMCF‐BM. After the first experiments were conducted in 2006, the facility has seen a sharp increase in usage and has produced a significant amount of data for the Canadian crystallographic community. Upgrades aimed at increasing throughput and flux to support the next generation of more demanding experiments are currently under way or have recently been completed. At CMCF‐BM, this includes an enhanced monochromator, automounter software upgrades and a much faster detector. CMCF‐ID will receive a major upgrade including a new undulator, a new monochromator and new optics to stably focus the beam onto a smaller sample size, as well as a brand‐new detector.