Celiac plexus block with botulinum toxin in severe chronic pancreatitis—A case report. (21st May 2020)

• Record Type: Journal Article
• Authors: Cho, Noo Ree; Kim, Yoo Na; Kim, Ji Yeong; Ko, Yu Ri; Hong, Tae Ho; Moon, Hyun Kyung; Park, Hue Jung
• Is Part Of: Journal of clinical pharmacy and therapeutics. Volume 45:Number 4(2020)
• Page Start: 848
• Page End: 851
• Publication Date: 2020-05-21
• Subjects: botulinum toxin -- celiac plexus block -- chronic pancreatitis -- pain; Clinical pharmacology -- Periodicals; Chemotherapy -- Periodicals; 615
• DOI: 10.1111/jcpt.13180
• Languages: English
• ISSNs: 0269-4727

Abstract

Abstract: What is known and objective: The botulinum toxin (BoNT) has been widely used for various conditions associated with pain. Case description: Here, we report a case where celiac plexus block (CPB) with BoNT relieved intractable chronic pancreatic pain without complications. CPB was performed at the L1 level under fluoroscopic guidance, and 50 IU BoNT was injected on each side. After 15 weeks, pain was decreased to 0/10 on a visual analogue scale, without opioids or tramadol. What is new and conclusion: Our case demonstrates the efficacy of CPB with BoNT in intractable pain due to severe chronic pancreatitis. Abstract : Botulinum toxin (BoNT) has been widely used in various pain diseases. Here, we report a case that CPB with 50 IU BoNT relieved intractable chronic pancreatic pain without complication.