Cancer Immunotherapy: Necroptosis‐Inducible Polymeric Nanobubbles for Enhanced Cancer Sonoimmunotherapy (Adv. Mater. 16/2020). Issue 16 (21st April 2020)

• Record Type: Journal Article
• Authors: Um, Wooram; Ko, Hyewon; You, Dong Gil; Lim, Seungho; Kwak, Gijung; Shim, Man Kyu; Yang, Suah; Lee, Jeongjin; Song, Yeari; Kim, Kwangmeyung; Park, Jae Hyung
• Is Part Of: Advanced materials. Volume 32:Issue 16(2020)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2020-04-21
• Subjects: damage‐associated molecular patterns -- immune checkpoint blockade -- necroptosis -- reactive oxygen species -- sonodynamic therapy; Materials -- Periodicals; Chemical vapor deposition -- Periodicals; 620.11
• DOI: 10.1002/adma.202070121
• Languages: English
• ISSNs: 0935-9648

Abstract

Abstract : In article number 1907953, Jae Hyung Park and co‐workers present the potential of necroptosis‐inducible nanobubbles for cancer immunotherapy. When exposed to ultrasound, nanobubbles promote release of intact damage‐associated molecular patterns and tumor‐associated antigens by inducing cell membrane rupture, facilitating efficient maturation of the dendritic cell for antitumor immune response.