Management of central nervous system relapse in a young patient affected by primary mediastinal large B‐cell lymphoma: A case report. Issue 6 (8th April 2020)

• Record Type: Journal Article
• Authors: Marangon, Miriam; Casadei, Beatrice; Broccoli, Alessandro; Argnani, Lisa; Cavo, Michele; Zinzani, Pier Luigi
• Is Part Of: Clinical case reports. Volume 8:Issue 6(2020)
• Page Start: 933
• Page End: 937
• Publication Date: 2020-04-08
• Subjects: autologous stem cell transplant -- central nervous system involvement -- MATRix regimen -- primary mediastinal large B‐cell lymphoma; Medicine -- Periodicals; 616.09
• DOI: 10.1002/ccr3.2706
• Languages: English
• ISSNs: 2050-0904

Abstract

Abstract: In primary mediastinal large B‐cell lymphoma, central nervous system (CNS) relapse is an uncommon event with a dismal prognosis. We report about the successful management of CNS relapse with chemoimmunotherapy according to MATRix (methotrexate, cytarabine, thiotepa, and rituximab) protocol followed by autologous stem cell transplant. Abstract : In primary mediastinal large B‐cell lymphoma, central nervous system (CNS) relapse is an uncommon event with a dismal prognosis. We report about the successful management of CNS relapse with chemoimmunotherapy according to MATRix (methotrexate, cytarabine, thiotepa, and rituximab) protocol followed by autologous stem cell transplant.