Nuclear Mechanics: Nuclear Mechanics within Intact Cells Is Regulated by Cytoskeletal Network and Internal Nanostructures (Small 18/2020). Issue 18 (7th May 2020)

• Record Type: Journal Article
• Authors: Zhang, Jitao; Alisafaei, Farid; Nikolić, Miloš; Nou, Xuefei A.; Kim, Hanyoup; Shenoy, Vivek B.; Scarcelli, Giuliano
• Is Part Of: Small. Volume 16:Issue 18(2020)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2020-05-07
• Subjects: Brillouin microscopy -- chemomechanical modeling -- cytoskeletal network -- nanostructures -- nuclear mechanics; Nanotechnology -- Periodicals; Nanoparticles -- Periodicals; Microtechnology -- Periodicals; 620.5
• DOI: 10.1002/smll.202070098
• Languages: English
• ISSNs: 1613-6810

Abstract

Abstract : In article number 1907688, Vivek B. Shenoy, Giuliano Scarcelli, and co‐workers use all‐optical Brillouin microscopy and 3D chemomechanical modeling to investigate the regulation of nuclear mechanics. It is observed that the nuclear modulus can be modulated by both epigenetic regulation targeting internal nanostructures and cytoskeletal behavior through a robust mechanism conserved in different culturing conditions.