Which types of mental work demands may be associated with reduced risk of dementia?. Issue 4 (28th September 2016)

• Record Type: Journal Article
• Authors: Then, Francisca S.; Luck, Tobias; Heser, Kathrin; Ernst, Annette; Posselt, Tina; Wiese, Birgitt; Mamone, Silke; Brettschneider, Christian; König, Hans‐Helmut; Weyerer, Siegfried; Werle, Jochen; Mösch, Edelgard; Bickel, Horst; Fuchs, Angela; Pentzek, Michael; Maier, Wolfgang; Scherer, Martin; Wagner, Michael; Riedel‐Heller, Steffi G.; Abholz, Heinz‐Harald; Brettschneider, Christian; Bachmann, Cadja; Bickel, Horst; Blank, Wolfgang; van den Bussche, Hendrik; Eifflaender‐Gorfer, Sandra; Eisele, Marion; Ernst, Annette; Fuchs, Angela; Heser, Kathrin; Jessen, Frank; Kaduszkiewicz, Hanna; Kaufeler, Teresa; Köhler, Mirjam; König, Hans‐Helmut; Koppara, Alexander; Lange, Carolin; Lubisch, Diana; Luck, Tobias; Luppa, Melanie; Maier, Wolfgang; Mayer, Manfred; Mösch, Edelgard; Pentzek, Michael; Posselt, Tina; Prokein, Jana; Riedel‐Heller, Steffi; Röhr, Susanne; Scherer, Martin; Schumacher, Anna; Stein, Janine; Steinmann, Susanne; Tebarth, Franziska; Wagner, Michael; Weckbecker, Klaus; Weeg, Dagmar; Werle, Jochen; Weyerer, Siegfried; Wiese, Birgitt; Wolfsgruber, Steffen; Zimmermann, Thomas; van den Bussche, Hendrik; Maier, Wolfgang; Scherer, Martin;
• Is Part Of: Alzheimer's & dementia. Volume 13:Issue 4(2017)
• Page Start: 431
• Page End: 440
• Publication Date: 2016-09-28
• Subjects: Dementia -- Cognitive functioning -- Cognitive reserve -- Mental demands -- Work environment -- Risk factors -- Longitudinal cohort study; Alzheimer's disease -- Periodicals; Alzheimer Disease -- Periodicals; Dementia -- Periodicals; Démence; Maladie d'Alzheimer; Périodique électronique (Descripteur de forme); Ressource Internet (Descripteur de forme); 616.83
• DOI: 10.1016/j.jalz.2016.08.008
• Languages: English
• ISSNs: 1552-5260

Abstract

Abstract : Introduction: Previous studies have demonstrated that an overall high level of mental work demands decreased dementia risk. In our study, we investigated whether this effect is driven by specific mental work demands and whether it is exposure dependent. Methods: Patients aged 75+ years were recruited from general practitioners and participated in up to seven assessment waves (every 1.5 years) of the longitudinal AgeCoDe study. Analyses of the impact of specific mental work demands on dementia risk were carried out via multivariate regression modeling (n = 2315). Results: We observed a significantly lower dementia risk in individuals with a higher level of "information processing" (HR, 0.888), "pattern detection" (HR, 0.878), "mathematics" (HR, 0.878), and "creativity" (HR, 0.878). Yet, exposure‐dependent effects were only significant for "information processing" and "pattern detection." Discussion: Our longitudinal observations suggest that dementia risk may be reduced by some but not all types of mental work demands.