Evolution of highly pathogenic H7N3 avian influenza viruses in Mexico. (7th January 2020)

• Record Type: Journal Article
• Authors: Trovão, Nídia Sequeira; Talavera, Guadalupe Ayora; Nelson, Martha I.; Perez de la Rosa, Juan Diego
• Is Part Of: Zoonoses and public health. Volume 67:Number 3(2020)
• Page Start: 318
• Page End: 323
• Publication Date: 2020-01-07
• Subjects: avian influenza virus -- BEAST -- evolutionary dynamics -- H7N3 -- H7N3 subtype -- influenza in birds -- phylogenetics; Zoonoses -- Periodicals; Public health -- Periodicals; 636.0896959
• DOI: 10.1111/zph.12673
• Languages: English
• ISSNs: 1863-1959

Abstract

Abstract: Highly pathogenic H7N3 influenza A viruses have persisted in poultry in Mexico since 2012, diversifying into multiple lineages that have spread to three Mexican states, as of 2016. The H7N3 viruses segregate into three distinct clades that are geographically structured. All 2016 viruses are resistant to adamantane antiviral drugs and have an extended 24‐nucleotide insertion at the HA cleavage site that was acquired from host 28S ribosomal RNA.