Antibiotic Resistance: Photo‐Disassembly of Membrane Microdomains Revives Conventional Antibiotics against MRSA (Adv. Sci. 6/2020). Issue 6 (18th March 2020)

• Record Type: Journal Article
• Authors: Hui, Jie; Dong, Pu‐Ting; Liang, Lijia; Mandal, Taraknath; Li, Junjie; Ulloa, Erlinda R.; Zhan, Yuewei; Jusuf, Sebastian; Zong, Cheng; Seleem, Mohamed N.; Liu, George Y.; Cui, Qiang; Cheng, Ji‐Xin
• Is Part Of: Advanced science. Volume 7:Issue 6(2020)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2020-03-18
• Subjects: antibiotic resistance -- membrane microdomains -- pulsed lasers -- Staphylococcus aureus -- staphyloxanthin; Science -- Periodicals; 505
• DOI: 10.1002/advs.202070035
• Languages: English
• ISSNs: 2198-3844

Abstract

Abstract : In article number 1903117, Ji‐Xin Cheng and co‐workers report an endogenous chromophore‐based phototherapy platform to combat antibiotic‐resistance Staphylococcus aureus infections. Functional membrane microdomains of Staphylococcus aureus are catastrophically disrupted via photochemical decomposition of membrane‐bound carotenoid pigment, staphyloxanthin, thus reviving a broad spectrum of conventional antibiotics against Staphylococcus aureus .