P1‐484: DIABETES IN PRECLINICAL AD DOWNREGULATES ANXIETY AND RELATED AFFECT TASK FMRI ACTIVITY IN MIDLIFE, THEN POTENTIATES EMOTIONAL DYSFUNCTION IN LATE LIFE. (1st July 2019) - Willette, Auriel A.; Pappas, Colleen; Wolf, Tovah; Klinedinst, Brandon S.; McLimans, Kelsey E.; Plagman, Alexandra K.; Le, Scott T.; Wang, Qian