A review of electroretinography waveforms and models and their application in the dog. (20th March 2020)

• Record Type: Journal Article
• Authors: Pasmanter, Nathaniel; Petersen‐Jones, Simon M.
• Is Part Of: Veterinary ophthalmology. Volume 23:Number 3(2020)
• Page Start: 418
• Page End: 435
• Publication Date: 2020-03-20
• Subjects: a‐wave -- dog -- electroretinography -- models -- PRA -- review; Veterinary ophthalmology -- Periodicals; 636.08977
• DOI: 10.1111/vop.12759
• Languages: English
• ISSNs: 1463-5216

Abstract

Abstract: Electroretinography (ERG) is a commonly used technique to study retinal function in both clinical and research ophthalmology. ERG responses can be divided into component waveforms, analysis of which can provide insight into the health and function of different types and populations of retinal cells. In dogs, ERG has been used in the characterization of normal retinal function, as well as the diagnosis of retinal diseases and measuring effects of treatment. While many components of the recorded waveform are similar across species, dogs have several notable features that should be differentiated from the responses in humans and other animals. Additionally, modifications of standard protocols, such as changing flash frequency and stimulus color, and mathematical models of ERG waveforms have been used in studies of human retinal function but have been infrequently applied to visual electrophysiology in dogs. This review provides an overview of the origins and applications of ERG in addition to potential avenues for further characterization of responses in the dog.