Therapeutic plasma exchange for exogenous insulin antibody syndrome in combined variable immunodeficiency: a case report. Issue 2 (25th January 2020)

• Record Type: Journal Article
• Authors: Robbins, Daniel J.; Taylor, Natalie E.; Narayanan, Damodaran; Hess, Aaron S.; Rose, William N.
• Is Part Of: Journal of clinical apheresis. Volume 35:Issue 2(2020)
• Page Start: 128
• Page End: 130
• Publication Date: 2020-01-25
• Subjects: common variable immune deficiency -- diabetes -- exogenous insulin antibody syndrome -- therapeutic plasma exchange; Hemapheresis -- Periodicals; Blood -- Transfusion -- Periodicals; Blood -- Transfusion, Autologous -- Periodicals; Cell separation -- Periodicals; Leukapheresis -- Periodicals; Plasmapheresis -- Periodicals; 615.39
• DOI: 10.1002/jca.21769
• Languages: English
• ISSNs: 0733-2459

Abstract

Abstract: A 32‐year‐old male with type I diabetes presented with profound hypoglycemia due to exogenous insulin antibody syndrome in the setting of newly‐diagnosed common variable immunodeficiency. Immunomodulatory therapy was not initially effective, but after the initiation of plasma exchange hypoglycemia resolved, and glucose lability improved.