Clinical Trials and Basic Research in Photodynamic Diagnostics and Therapies from the Center for Laser Diagnostics and Therapy in Poland. (29th April 2020)

• Record Type: Journal Article
• Authors: Kawczyk‐Krupka, Aleksandra; Bartusik‐Aebisher, Dorota; Latos, Wojciech; Cieślar, Grzegorz; Sieroń, Karolina; Kwiatek, Sebastian; Oleś, Piotr; Kwiatek, Beata; Aebisher, David; Krupka, Magdalena; Wiench, Rafał; Skaba, Dariusz; Olek, Marcin; Kasperski, Jacek; Czuba, Zenon; Sieroń, Aleksander
• Other Names: Hasan Tayyaba guestEditor.; Kessel David guestEditor.; Greer Alexander guestEditor.
• Is Part Of: Photochemistry and photobiology. Volume 96:Number 3(2020)
• Page Start: 539
• Page End: 549
• Publication Date: 2020-04-29
• Subjects: Photochemistry -- Periodicals; Light -- Physiological effect -- Periodicals; 541.35
• DOI: 10.1111/php.13243
• Languages: English
• ISSNs: 0031-8655

Abstract

Abstract: The purpose of this review is to present an overview of the development of photodiagnostic and photodynamic therapy (PDD and PDT) techniques in Poland. The paper discusses the principles of PDD, including fluorescent techniques in determining precancerous conditions and cancers of the skin, digestive tract, bladder and respiratory tract. Methods of PDT of cancer will be discussed and the current state of knowledge as well as future trends in the development of photodynamic techniques will be presented, including the possibility of using photodynamic antimicrobial therapy. Research pioneers in photodynamic medicine such as Thomas Dougherty are an inspiration for the development of methods of PDD and PDT in our Clinic. The Center for Laser Diagnostics and Therapy in Bytom, Poland, promotes the propagation of PDD and PDT through the training of clinicians and raising awareness among students in training and the general public. Physicians at the Center are engaged in photomedical research aimed at clinical implementation and exploration of new avenues in photomedicine while optimizing existing modalities. The Center promotes dissemination of clinical results from a wide range of topics in PDD and PDT and serving as representative authorities of photodynamic medicine in Poland and Europe. Abstract : The purpose of this review is to present an overview of the development of photodiagnostic and photodynamic therapy (PDD and PDT) techniques in Poland. Research pioneers in photodynamic medicine such as Thomas Dougherty are an inspiration for the development of PDD and PDT in our Clinic. The paper presents the use of PDD and PDT in everyday medical practice and also the results of basic research aimed at determining the mechanisms of photodynamic therapy at the cell level. The Center promotes also dissemination of clinical results from a wide range of topics in PDD and PDT in Poland and Europe.