Polymeric Nanoparticles: Polymeric Nanoparticles with Neglectable Protein Corona (Small 18/2020). Issue 18 (7th May 2020)

• Record Type: Journal Article
• Authors: Alberg, Irina; Kramer, Stefan; Schinnerer, Meike; Hu, Qizhi; Seidl, Christine; Leps, Christian; Drude, Natascha; Möckel, Diana; Rijcken, Cristianne; Lammers, Twan; Diken, Mustafa; Maskos, Michael; Morsbach, Svenja; Landfester, Katharina; Tenzer, Stefan; Barz, Matthias; Zentel, Rudolf
• Is Part Of: Small. Volume 16:Issue 18(2020)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2020-05-07
• Subjects: asymmetrical flow field‐flow fractionation -- drug delivery -- micellar structures -- protein corona; Nanotechnology -- Periodicals; Nanoparticles -- Periodicals; Microtechnology -- Periodicals; 620.5
• DOI: 10.1002/smll.202070100
• Languages: English
• ISSNs: 1613-6810

Abstract

Abstract : Currently it is assumed that each nanoparticle rapidly adsorbs proteins when it enters the living organism. However, this is not a general property of all nanosized drug delivery systems. In article number 1907574, Stefan Tenzer, Matthias Barz, Rudolf Zentel, and co‐workers present three self‐assembled polymeric structures, which are effectively free of a protein corona and additionally show prolonged circulation profiles in vivo.