Capillary Alignment: Collagen Microfibers Induce Blood Capillary Orientation and Open Vascular Lumen (Adv. Biosys. 5/2020). Issue 5 (13th May 2020)

• Record Type: Journal Article
• Authors: Liu, Hao; Kitano, Shiro; Irie, Shinji; Levato, Riccardo; Matsusaki, Michiya
• Is Part Of: Advanced biosystems. Volume 4:Issue 5(2020)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2020-05-13
• Subjects: Biological systems -- Periodicals; Biotechnology -- Periodicals; Bioengineering -- Periodicals; Biomedical engineering -- Periodicals; Biological Science Disciplines; Periodicals; Periodicals; 660.6
• DOI: 10.1002/adbi.202070052
• Languages: English
• ISSNs: 2366-7478

Abstract

Abstract : In article number 2000038, Michiya Matsusaki and co‐workers demonstrate a method based on high water‐dispersible collagen microfibers (CMF‐20) to fabricate 3D blood capillary tissues, which a provides homogenous tissue structure. The CMF‐20 acts as a microscaffold to support endothelial cell migration and maturation, thus forming the vascular lumen. The aligned CMF‐20 is produced by shear force, guiding the formation of an oriented capillary network.