Front Cover: One Guest or Two? A Crystallographic and Solution Study of Guest Binding in a Cubic Coordination Cage (Chem. Eur. J. 14/2020). Issue 14 (6th February 2020)

• Record Type: Journal Article
• Authors: Taylor, Christopher G. P.; Argent, Stephen P.; Ludden, Michael D.; Piper, Jerico R.; Mozaceanu, Cristina; Barnett, Sarah A.; Ward, Michael D.
• Is Part Of: Chemistry. Volume 26:Issue 14(2020)
• Page Start: 2980
• Page End: 2980
• Publication Date: 2020-02-06
• Subjects: binding constants -- coordination cage -- host–guest chemistry -- supramolecular chemistry -- X-ray crystallography; Chemistry -- Periodicals; 540
• DOI: 10.1002/chem.201905700
• Languages: English
• ISSNs: 0947-6539

Abstract

Abstract : The ability of coordination cages to accommodate guests in their cavities is crucial to functions relating to catalysis, sensing and drug delivery. Consequently, understanding properly the number and type of guests that can bind is essential for development of new functions. In this work we show how a series of guests which apparently give 1:1 H ⋅G binding in a cage according to titrations performed in dilute solution show, in the solid state, 1:2 H ⋅G2 complex formation with the pairs of bound guests giving very high packing coefficients (up to 87 %). More information can be found in the Full Paper by M. D. Ward et al. on page 3054 .