Epidemiological study on the relationship between toxin production and psm‐mec mutations in MRSA isolates in Thailand. (5th February 2020)

• Record Type: Journal Article
• Authors: Tabuchi, Fumiaki; Lulitanond, Aroonlug; Lulitanond, Viraphong; Thunyaharn, Sudaluck; Kaito, Chikara
• Is Part Of: Microbiology and immunology. Volume 64:Number 3(2020)
• Page Start: 219
• Page End: 225
• Publication Date: 2020-02-05
• Subjects: MRSA -- psm‐mec -- SCCmec -- toxin -- virulence; Microbiology -- Periodicals; Immunology -- Periodicals; Allergy and Immunology -- Periodicals; Microbiology -- Periodicals; Microbiologie -- Périodiques; Immunologie -- Périodiques; 579
• DOI: 10.1111/1348-0421.12764
• Languages: English
• ISSNs: 0385-5600

Abstract

Abstract: In this present study, we investigated the phenol‐soluble modulin ( psm‐mec ) mutations, the staphylococcal cassette chromosome mec (SCC mec ) types, and toxin production in 102 methicillin‐resistant Staphylococcus aureus (MRSA) isolates from the northeast and central regions of Thailand. The MRSA isolates carrying ‐7T>C psm‐mec in Type II SCC mec ( n = 18) and the MRSA isolates carrying no psm‐mec in Type IV ( n = 8) or Type IX SCC mec ( n = 4) had higher hemolytic activity against sheep erythrocytes than MRSA isolates carrying intact psm‐mec in Type III SCC mec ( n = 34), but MRSA isolates carrying no psm‐mec in Type I SCC mec ( n = 27) did not.