FeIII–Salen‐Based Probes for the Selective and Sensitive Detection of E450 in Foodstuff. Issue 25 (15th April 2020)

• Record Type: Journal Article
• Authors: Yadav, Prerna; Jakubaszek, Marta; Spingler, Bernhard; Goud, Bruno; Gasser, Gilles; Zelder, Felix
• Is Part Of: Chemistry. Volume 26:Issue 25(2020)
• Page Start: 5717
• Page End: 5723
• Publication Date: 2020-04-15
• Subjects: disassembly approach -- E450 -- fluorescence -- iron -- pyrophosphate (PPi) -- salen complexes -- selective detection; Chemistry -- Periodicals; 540
• DOI: 10.1002/chem.201905686
• Languages: English
• ISSNs: 0947-6539

Abstract

Abstract: Inorganic pyrophosphate (PPi) is considered as a diagnostic marker for various diseases such as cancer and vascular calcification. PPi also plays an important preservative role as an additive E450 in foodstuff. In this work, a selective Fe III –salen‐based probe for PPi is described; this probe disassembles in the presence of the target analyte into its molecular blocks, 1, 2‐propanediamine and 3‐chloro‐5‐formyl‐4‐hydroxybenzenesulfonic acid. The latter signaling unit leads to a fluorometric response. Compared with a related prototype, the new complex shows a 2.3‐times stronger emission at 500 nm and a 155‐times better selectivity of PPi over adenosine triphosphate (ATP). Importantly, the new probe was successfully applied for detecting E450 in foodstuff. Abstract : Selective brightness : A selective Fe III –salen‐based probe that fluorometrically detects pyrophosphate (alias E450) in baking powder by a disassembly approach is described.