Diagnosis of exon 12‐positive polycythemia vera rescued by NGS. Issue 5 (21st March 2020)

• Record Type: Journal Article
• Authors: Geay, Antoine; Aral, Bernard; Bourgeois, Valentin; Martin, Pauline; Airaud, Fabrice; Garrec, Céline; Bézieau, Stéphane; Gardie, Betty; Girodon, François
• Is Part Of: Clinical case reports. Volume 8:Issue 5(2020)
• Page Start: 790
• Page End: 792
• Publication Date: 2020-03-21
• Subjects: erythrocytosis -- Exon 12 -- JAK2 -- next generation sequencing -- polycythemia vera; Medicine -- Periodicals; 616.09
• DOI: 10.1002/ccr3.2720
• Languages: English
• ISSNs: 2050-0904

Abstract

Abstract: A JAK2 V617F‐negative polycythemia associated with low serum epo needs to be tested for an exon 12 JAK2 mutation. When negative, due to potential serious complications in PV, a next generation sequencing is necessary to rule out false negative results. Abstract : A JAK2 V617F‐negative polycythemia associated with low serum epo needs to be tested for an exon 12 JAK2 mutation. When negative, due to potential serious complications in PV, a next generation sequencing is necessary to rule out false negative results.