Metabolomics study of different parts of licorice from different geographical origins and their anti‐inflammatory activities. Issue 8 (26th February 2020)

• Record Type: Journal Article
• Authors: Bai, Haiying; Bao, Fang; Fan, Xiaorui; Han, Shu; Zheng, Wenhui; Sun, Lili; Yan, Na; Du, Hong; Zhao, Haiyu; Yang, Zhigang
• Is Part Of: Journal of separation science. Volume 43:Issue 8(2020)
• Page Start: 1593
• Page End: 1602
• Publication Date: 2020-02-26
• Subjects: anti‐inflammatory activity -- geographical origin -- licorice -- metabolomics -- traditional Chinese medicine; Separation (Technology) -- Periodicals; Chromatographic analysis -- Periodicals; 543.089
• DOI: 10.1002/jssc.201901013
• Languages: English
• ISSNs: 1615-9306

Abstract

Abstract: Glycyrrhiza uralensis Fisch., known as licorice, is one of the most famous traditional Chinese medicines. In this study, we perform a metabolome analysis using liquid chromatography–tandem mass spectrometry to assign bioactive components in different parts of licorice from different geographical origins in Gansu province of China. Sixteen potential biomarkers of taproots from different geographical origins were annotated, such as glycycoumarin, gancaonin Z, licoricone, and dihydroxy kanzonol H mainly exist in the sample of Jiuquan; neoliquiritin, 6′‐acetylliquiritin, licochalcone B, isolicoflavonol, glycyrol, and methylated uralenin mainly exist in Glycyrrhiza uralensis from Lanzhou; gancaonin L, uralenin, and glycybridin I mainly exist in licorice from Wuwei for the first time.