Auto‐Oxidative Povarov/Aromatization Tandem Reaction of Glycine Derivatives with Enamides: Acylamino as both Activating and Leaving Group. Issue 6 (18th May 2020)

• Record Type: Journal Article
• Authors: Huang, Songhai; Bao, Xiazhen; Fu, Ying; Zhang, Yongxin; Quan, Zhengjun; Huo, Congde
• Is Part Of: Asian journal of organic chemistry. Volume 9:Issue 6(2020)
• Page Start: 925
• Page End: 928
• Publication Date: 2020-05-18
• Subjects: auto-oxidation -- tandem reaction -- glycine derivatives -- enamides -- quinolines; Chemistry, Organic -- Periodicals; Organic compounds -- Synthesis -- Periodicals; 547.005
• DOI: 10.1002/ajoc.202000191
• Languages: English
• ISSNs: 2193-5807

Abstract

Abstract: The auto‐oxidative Povarov/aromatization tandem reaction of N‐aryl glycine derivatives with enamides yields a series of complex quinoline derivatives in good yields. The reactions are performed using only catalytic amount of Brønsted acid and O2 . The acylamino group is used as both activating and leaving group to improve the reaction efficiency in this transformation. Abstract : Cyclization : Auto‐oxidative Povarov/aromatization tandem reaction of N‐aryl glycine derivatives with enamides yields a series of complex quinoline derivatives in good yields. The reactions are performed using only catalytic amount of Brønsted acid and O2 . The acylamino group is used as both activating and leaving group to improve the reaction efficiency in this transformation