A comparative analysis of gene expression induced by the embryo in the caprine endometrium. Issue 2 (28th November 2019)

• Record Type: Journal Article
• Authors: Liu, Xiaorui; Zhang, Lei; Han, Jincheng; Yang, Lichun; Cui, Jiuzeng; Che, Sicheng; Cao, Binyun; Song, Yuxuan
• Is Part Of: Veterinary medicine and science. Volume 6:Issue 2(2020)
• Page Start: 196
• Page End: 203
• Publication Date: 2019-11-28
• Subjects: Dairy goats -- Differential expressed genes (DEGs) -- Endocytosis -- Endometrium; Veterinary medicine -- Periodicals; Animal Diseases; Veterinary medicine; Periodicals; Periodicals; 636.08905
• DOI: 10.1002/vms3.221
• Languages: English
• ISSNs: 2053-1095

Abstract

Abstract: Transcriptomics is an established powerful tool to identify potential mRNAs and ncRNAs (non‐coding RNAs) for endometrial receptivity. In this study, the goat endometrium at estrus day 5 (ED5) and estrus day 15 (ED15) were selected to systematically analyse the differential expressed genes (DEGs) what were induced by the embryo. There were 1, 847 genes which were significantly differential expressed in endometrium induced by the embryo at ED5, and 1, 346 at ED15 ( p ‐value < .05). Secreted phosphoprotein 1 ( SPP ) was the responsive genes for embryo in the goat endometrium during estrus cycle, neurotensis ( NTS ) and pleiotrophin ( PTN ) were the responsive genes for embryo in the goat endometrium at ED5, Testin ( TES ) and Phosphate and Tension Homology Deleted on Chromsome ten ( PTEN ) at ED15. Furthermore, Gene Ontology (GO) and Kyoto Encyclopedia of Genes (KEGG) analysis revealed cytoplasm and Endocytosis were indispensable for the endometrium development in dairy goat. In a word, this resulting view of the transcriptome greatly uncovered the global trends in mRNAs expression induced by the embryo in the endometrium of dairy goats. Abstract : In this study, the goat endometrium at estrus day 5 and estrus day 15 were selected to systematically analyse the DEGs induced by the embryo in the endometrium of dairy goats, and there were 1, 847 genes that were differential expressed at ED5, and 1, 346 at ED15. In a word, this resulting view of the transcriptome greatly uncovered the global trends in mRNAs expression induced by the embryo in the endometrium of dairy goats.