Cobalt‐Catalyzed Reductive Carboxylation of Aryl Bromides with Carbon Dioxide. Issue 12 (17th April 2020)

• Record Type: Journal Article
• Authors: Hang, Wei; Yi, Yaping; Xi, Chanjuan
• Is Part Of: Advanced synthesis & catalysis. Volume 362:Issue 12(2020)
• Page Start: 2337
• Page End: 2341
• Publication Date: 2020-04-17
• Subjects: Catalysis -- Aryl bromides -- Reductive carboxylation -- Carbon dioxide; Catalysis -- Periodicals; Organic compounds -- Synthesis -- Periodicals; Chemistry -- Periodicals; Chemistry, Technical -- Periodicals; Chemistry -- Periodicals; Catalysis -- Periodicals; Technology, Pharmaceutical -- Periodicals; 547.2
• DOI: 10.1002/adsc.202000301
• Languages: English
• ISSNs: 1615-4150

Abstract

Abstract: Cobalt‐catalyzed reductive carboxylation of aryl bromides with carbon dioxide has been developed. The reaction proceeded under one atm pressure of CO2 at 40 °C in the presence of cobalt iodide/2, 2′‐bipyridine catalysts and zinc dust as a reducing reagent. Various aryl bromides could be converted to the corresponding carboxylic acids in good to high yields. Preliminary mechanistic experiments ruled out intervention of intermediate organozinc species for carboxylation with CO2, thus suggesting a direct CO2 insertion into the corresponding ArCoBr species. Abstract :