Acute encephalopathy followed by delayed myelopathy: A rare presentation of organophosphate poisoning. (April 2020)

• Record Type: Journal Article
• Authors: Agarwal, Ayush; Garg, Divyani; Goyal, Vinay; VY, Vishnu; Singh, Mamta Bhushan; Srivastava, MV Padma
• Is Part Of: Tropical doctor. Volume 50:Number 2(2020)
• Page Start: 162
• Page End: 164
• Publication Date: 2020-04
• Subjects: Chlorpyriphos -- organophosphorus compounds -- myelopathy -- organophosphorus poisoning-induced delayed neurotoxicity (OPIND); Tropical medicine -- Periodicals; Medical care -- Developing countries -- Periodicals; Developing Countries -- Periodicals; Tropical Medicine -- Periodicals; Tropische geneeskunde; 616.9883
• DOI: 10.1177/0049475519899580
• Languages: English
• ISSNs: 0049-4755

Abstract

Organophosphorus compounds (OPC) are commonly used pesticides and suicidal ingestion is a common mode of poisoning. The manifestation of OPC poisoning and its severity depend upon the type, dose and potency of the OPC consumed. Neurological presentations are well defined clinical syndromes consisting of early, intermediate and delayed manifestations (rare), categorised on the basis of time elapsed since OPC exposure. We report a rare delayed manifestation of organophosphorus poisoning in the form of pure motor spastic paraparesis due to dorsal myelopathy. A possibility of delayed manifestations of toxicity should be considered in individuals presenting with features suggestive of myelopathy and a previous history of organophosphate exposure.