Follow-up of renal impairment results among attendees taking HIV Pre-Exposure Prophylaxis at a Sydney Sexual Health Clinic. (June 2020)

• Record Type: Journal Article
• Authors: Comninos, NB; Foster, R; Varma, R; Bourne, C
• Is Part Of: International journal of STD & AIDS. Volume 31:Number 7(2020)
• Page Start: 689
• Page End: 693
• Publication Date: 2020-06
• Subjects: Australia -- prevention -- human immunodeficiency virus; Sexually transmitted diseases -- Periodicals; AIDS (Disease) -- Periodicals; 616.951
• DOI: 10.1177/0956462420922751
• Languages: English
• ISSNs: 0956-4624

Abstract

Renal monitoring is recommended for Pre-Exposure Prophylaxis (PrEP) users. We aimed to explore follow-up and outcomes among PrEP users with renal impairment (defined as estimated glomerular filtration rate <65 mL/min/1.73 m 2 ) attending Sydney Sexual Health Centre. Time to follow-up was analysed for impairment results over a 12-month period (January–December 2018); 48/2504 (1.9%) tests among 1700 attendees showed impairment. Follow-up occurred in 39/48 (81.3%) impairment results after a median of 42 days. PrEP was ceased in 3/6 cases of non-resolving/persisting impairment, with one case of subsequent human immunodeficiency virus infection. Maintaining engagement and follow-up of those with renal impairment are important aspects of PrEP service provision.