Survival of Staphylococcus epidermidis in Propofol and Intralipid in the Dead Space of Intravenous Injection Ports. (July 2019)

• Record Type: Journal Article
• Authors: Noble, Ronan M. N.; Salim, Saad Y.; Walker, Bradley; Khadaroo, Rachel G.; Chiarella, Angelo B.; Gragasin, Ferrante S.; Bourque, Stephane L.
• Is Part Of: Anesthesia & analgesia. Volume 129:Number 1(2019)
• Publication Date: 2019-07
• Subjects: Anesthesiology -- Periodicals; Anesthesia; Anesthesiology; Analgesia; Analgesics; Anesthesiology -- Periodicals; 617.9605
• DOI: 10.1213/ANE.0000000000002654
• Languages: English
• ISSNs: 0003-2999

Abstract

Abstract : We tested whether propofol or Intralipid inoculated with Staphylococcus epidermidis would promote bacterial growth within an intravenous (IV) injection hub, a site prone to bacterial contamination. In tubes incubated under optimal conditions, S epidermidis exhibited growth in Intralipid, but not in propofol. In contrast, within the IV hub incubated with either propofol or intralipid at room temperature, S epidermidis bacterial numbers declined with time, and virtually no contamination remained after 12 hours. These data suggest that certain IV lines are inhospitable for S epidermidis .