Focused ultrasound thalamotomy for multiple sclerosis–associated tremor. (June 2020)

• Record Type: Journal Article
• Authors: Máñez-Miró, Jorge U; Martínez-Fernández, Raúl; del Alamo, Marta; Pineda-Pardo, José A; Fernández-Rodríguez, Beatriz; Alonso-Frech, Fernando; Álvarez-Cermeño, Jose Carlos; Obeso, José A
• Is Part Of: Multiple sclerosis. Volume 26:Number 7(2020)
• Page Start: 855
• Page End: 858
• Publication Date: 2020-06
• Subjects: Tremor -- focused ultrasound -- multiple sclerosis -- thalamotomy; Central nervous system -- Diseases -- Periodicals; Myelin sheath -- Diseases -- Periodicals; Inflammation -- Periodicals; Multiple sclerosis -- Periodicals; Central Nervous System Diseases -- Periodicals; Demyelinating Diseases -- Periodicals; Inflammation -- Periodicals; Multiple Sclerosis -- Periodicals; Système nerveux central -- Maladies -- Périodiques; Gaine de myéline -- Maladies -- Périodiques; Inflammation (Pathologie) -- Périodiques; Sclérose en plaques -- Périodiques; Electronic journals; 616.834005
• DOI: 10.1177/1352458519861597
• Languages: English
• ISSNs: 1352-4585

Abstract

Multiple sclerosis (MS)-related tremor is frequent and can often be refractory to medical treatment, which makes it a potential source of major disability. Functional neurosurgery approaches such as thalamic deep brain stimulation (DBS) or radiofrequency thalamotomy are proven to be effective, but the application of invasive techniques in MS tremor has so far been limited. Magnetic resonance (MR)-guided focused ultrasound thalamotomy, which has already been approved for treating essential and parkinsonian tremor, provides a minimally invasive approach that could be useful in the management of MS tremor. We report for the first time a patient with medically refractory MS-associated tremor successfully treated by focused ultrasound thalamotomy.