Prevalence and risk factors of strongyloidiasis in patients with systemic lupus erythematosus in Southern Thailand. (May 2020)

• Record Type: Journal Article
• Authors: Juthong, Siriporn; Geater, Alan F.; Dekumyoy, Paron; Hortiwakul, Thanaporn; Siripaitoon, Boonjing; Aiewruengsurat, Duangkamol; Thongbun, Nannapas
• Is Part Of: Lupus. Volume 29:Number 6(2020)
• Page Start: 539
• Page End: 546
• Publication Date: 2020-05
• Subjects: Systemic lupus erythematosus -- strongyloidiasis -- Strongyloides stercoralis -- risk factors -- Thailand; Systemic lupus erythematosus -- Periodicals; 616.772005
• DOI: 10.1177/0961203320911091
• Languages: English
• ISSNs: 0961-2033

Abstract

Background: Strongyloidiasis can be fatal in systemic lupus erythematosus (SLE) patients, but few epidemiological studies have investigated the burden of this tropical disease among the SLE population. This study aimed to assess the prevalence and associated factors of strongyloidiasis among SLE patients in Southern Thailand. Methods: A cross-sectional study was conducted on 180 SLE patients attending the Rheumatology Clinic at Songklanagarind Hospital. Stool specimens were collected and examined using the direct smear technique and agar plate culture technique. Serum anti- Strongyloides stercoralis IgG was measured by IgG-ELISA. Results: The overall prevalence of strongyloidiasis by combined parasitologyl and/or serology was 15.6%. The prevalence of strongyloidiasis by parasitological methods was 2.2%. Positive parasitology and/or serology was associated with male sex and a SLE disease duration of less than two years. Conclusion: Strongyloidiasis is highly prevalent among the SLE population. A combination of serological and parasitological methods increases the rate of diagnosis of strongyloidiasis in SLE patients.