Clinical research on individualized hemodialysis preventing unconventional hypotension in diabetic nephropathy patient. Issue 4 (April 2020)

• Record Type: Journal Article
• Authors: Li, Wen-Hong; Yin, Yu-Min; Chen, Hao; Rui, Zhang-Ru; Yuan, Yang; Yun, He; Wang, Jin-Wen
• Is Part Of: International journal of artificial organs. Volume 43:Issue 4(2020)
• Page Start: 229
• Page End: 233
• Publication Date: 2020-04
• Subjects: Intradialytic hypotension -- low-temperature model -- sodium model -- pattern of step ultrafiltration -- dialysate-containing glucose -- individualized treatment; Artificial organs -- Periodicals; 617.956
• DOI: 10.1177/0391398819882697
• Languages: English
• ISSNs: 0391-3988

Abstract

Objective: This study aims to evaluate the effectiveness of individualized hemodialysis for unconventional hypotension in diabetic nephropathy patients. Methods: A total of 60 patients were selected and randomly divided into study group and control group. The control group used the standard dialysis model, while the study group used the individualized hemodialysis scheme, in which the dialysis was performed using an individualized dialysis machine temperature control, pattern of natrium, and pattern of step ultrafiltration in combination with dialysate-containing glucose. Results: The total occurrence rate of hypotension, dry weight standard-reaching rate, and blood quality during and after dialysis in the study group were superior to those in the control group ( P < 0.05). Furthermore, the symptom scores in the study group (dizziness score, chest distress score, sweating score, muscle spasm score, gastrointestinal symptom score, and temporary mind change score) were lower than those in the control group ( P < 0.05). The serum sodium, potassium, and chloride concentration in these two groups after dialysis was not statistically different ( P > 0.05). Conclusion: The combined application of low temperature, pattern of natrium, pattern of step ultrafiltration, and dialysate-containing glucose individualization is safe and effective for preventing and controlling the occurrence of intradialytic hypotension (IDH), improve symptoms, and improve the dry weight standard-reaching rate.