Usefulness of Diffusion-Weighted Magnetic Resonance Imaging Using Apparent Diffusion Coefficient Values for Diagnosis of Infantile Hemangioma. Issue 4 (July 2019)

• Record Type: Journal Article
• Authors: Saito, Mioko; Kitami, Masahiro; Takase, Kei
• Is Part Of: Journal of computer assisted tomography. Volume 43:Issue 4(2019)
• Publication Date: 2019-07
• Subjects: child -- diffusion magnetic resonance imaging -- sarcoma -- infantile hemangioma -- apparent diffusion coefficient values; Tomography -- Periodicals; Tomography -- Periodicals; Tomography; Periodicals; 616.0757
• DOI: 10.1097/RCT.0000000000000884
• Languages: English
• ISSNs: 0363-8715

Abstract

Abstract : Objective: The objective of this study was to determine whether apparent diffusion coefficient (ADC) values obtained from diffusion-weighted imaging allow differentiation between infantile hemangiomas (IHs) and malignant soft tissue tumors. Methods: A retrospective review was performed on magnetic resonance images of pediatric patients with IHs and malignant soft tissue tumors from January 2014 to December 2016, which comprised 7 patients with 8 IHs and 6 patients with 6 malignant soft tissue tumors. We calculated and compared the ADC values of each lesion. Receiver operating characteristic curve analysis was performed to determine a cutoff value for the ADC. Results: There was a statistically significant difference between the ADC values of IHs and those of malignant soft tissue tumors (1.32 [1.27–1.72] × 10 −3 mm 2 /s vs 0.67 [0.57–0.79] × 10 −3 mm 2 /s; P < 0.001), with no overlap between the 2 groups. Conclusions: The ADC values obtained from diffusion-weighted imaging were useful in differentiating IHs from malignant soft tissue tumors in pediatric patients.