HIV incidence during breastfeeding and mother-to-child transmission in Cape Town, South Africa. (1st July 2019)

• Record Type: Journal Article
• Authors: le Roux, Stanzi M.; Abrams, Elaine J.; Nguyen, Kelly K.; Myer, Landon
• Is Part Of: AIDS. Volume 33:Number 8(2019)
• Publication Date: 2019-07-01
• Subjects: AIDS (Disease) -- Periodicals; Acquired Immunodeficiency Syndrome; AIDS (Disease); Periodicals; Periodicals; 616.9792005
• DOI: 10.1097/QAD.0000000000002224
• Languages: English
• ISSNs: 0269-9370

Abstract

Abstract : N/A: Despite widespread concerns about HIV incidence in pregnant and postpartum women, there are few data from Africa on HIV acquisition in breastfeeding and subsequent mother-to-child transmission. We measured HIV incidence in a prospective cohort of 413 peripartum and breastfeeding women who tested HIV-negative during pregnancy. In 377 woman-years accrued postpartum (median duration of follow-up, 1 year), there were seven women infected after delivery (postpartum incidence, 1.86/100 person-years; 95% confidence interval 0.88–3.89) with transmission to 2/7 (28%) infants.