Reduced Scan Time in 123I-FP-CIT SPECT Imaging Using a Large-Field Cadmium-Zinc-Telluride Camera. (July 2019)

• Record Type: Journal Article
• Authors: Bani Sadr, Alexandre; Testart, Nathalie; Tylski, Perrine; Scheiber, Christian
• Is Part Of: Clinical nuclear medicine. Volume 44:Number 7(2019)
• Publication Date: 2019-07
• Subjects: 123I-ioflupane SPECT -- CdZnTe -- parkinsonian disorders; Nuclear medicine -- Periodicals; Radioisotope scanning -- Periodicals; Nuclear Medicine -- Periodicals; 616.07575
• DOI: 10.1097/RLU.0000000000002554
• Languages: English
• ISSNs: 0363-9762

Abstract

Abstract : Abstract: We evaluated the reproducibility of 123 I-ioflupane ( 123 I-FP-CIT) SPECT with shorter scan times using a CZT camera. One hundred ninety-nine 123 I-FP-CIT SPECT scans obtained with standard scan time (30 minutes) were truncated to provide 24-, 18-, and 15-minute study simulations. Striatal binding ratios were automatically calculated and remained stable for all series. At 15 minutes, only 10 of 398 striata (2.5%) showed statistically significant different striatal binding ratios compared with reference series. These series were reviewed by 2 operators, and a perfect agreement was found for each patient. Therefore, CZT camera allows a 2-fold scan time reduction in 123 I-FP-CIT SPECT.