Lip and Perioral Enhancement With Hyaluronic Acid Dermal Fillers in Individuals With Skin of Color. Issue 7 (July 2019)

• Record Type: Journal Article
• Authors: Taylor, Susan C.; Downie, Jeanine B.; Shamban, Ava; Few, Julius; Weichman, Barry M.; Schumacher, Andrew; Gallagher, Conor J.
• Is Part Of: Dermatologic surgery. Volume 45:Issue 7(2019)
• Publication Date: 2019-07
• Subjects: Skin -- Surgery -- Periodicals; Skin -- Diseases -- Surgery -- Periodicals; 617.477
• DOI: 10.1097/DSS.0000000000001842
• Languages: English
• ISSNs: 1076-0512

Abstract

Abstract : BACKGROUND: Individuals with skin of color are underrepresented in studies of lip and perioral enhancement. OBJECTIVE: To examine the effectiveness and safety of hyaluronic acid (HA) dermal filler treatment for lip and perioral enhancement in subjects with skin of color. METHODS: Data were pooled from subjects with Fitzpatrick skin phototypes IV, V, or VI in 2 pivotal studies of HA dermal fillers. Photonumeric scales were used to assess lip fullness (5-point scale) and perioral lines and oral commissures severity (each 4-point scales). Safety was assessed by injection site responses recorded in patient diaries and adverse events (AEs). RESULTS: The cohort comprised 72 subjects (median age: 49.5 years; 95.8% female). Mean lip fullness improved from baseline by 1.1 points at 3 months after treatment; 85.0% of subjects were responders (≥1-point improvement). Of subjects treated for perioral lines ( n = 12) and oral commissures ( n = 56), 90.9% and 46.4%, respectively, were responders. Injection site responses were generally mild or moderate in severity, resolved within 2 weeks, and were consistent with those expected for HA dermal filler treatment. The most common AEs were injection site mass (19.4%) and bruising (12.5%). CONCLUSION: Lip and perioral enhancement with HA dermal fillers is effective and safe in subjects with skin of color.