A rare case of a gabapentin‐induced cardiomyopathy. (9th April 2019)

• Record Type: Journal Article
• Authors: Tellor, Katie B.; Ngo‐Lam, Richard; Badran, Dena; Armbruster, Anastasia L.; Schwarze, Martin W.
• Is Part Of: Journal of clinical pharmacy and therapeutics. Volume 44:Number 4(2019)
• Page Start: 644
• Page End: 646
• Publication Date: 2019-04-09
• Subjects: adverse effect -- cardiomyopathy -- cardiovascular disease; Clinical pharmacology -- Periodicals; Chemotherapy -- Periodicals; 615
• DOI: 10.1111/jcpt.12840
• Languages: English
• ISSNs: 0269-4727

Abstract

Summary: What is known and objective: Gabapentin, a γ‐aminobutyric acid derivative, is used for the treatment of partial onset seizures, postherpetic neuralgia, diabetic neuropathy and a host of other neurological disorders. Case description: A 44‐year‐old woman with spinal stenosis was prescribed gabapentin for pain. Two months after initiating therapy, she was diagnosed with a new‐onset non‐ischaemic cardiomyopathy with an ejection fraction of 36% measured on a transthoracic echocardiogram. What is new and Conclusion: A patient with suspected gabapentin‐induced cardiomyopathy is reported. However, to date, gabapentin therapy has not been associated with risk of the developing a cardiomyopathy.